The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2007

Filed:

Dec. 10, 2002
Applicants:

Ruxandra Draghia-akli, Houston, TX (US);

Robert H. Carpenter, Bastrop, TX (US);

Douglas R. Kern, The Woodlands, TX (US);

Robert J. Schwartz, Houston, TX (US);

Glen King, Rosharon, TX (US);

Kevin Hahn, Missouri City, TX (US);

Malcolm K. Brenner, Bellaire, TX (US);

Inventors:

Ruxandra Draghia-Akli, Houston, TX (US);

Robert H. Carpenter, Bastrop, TX (US);

Douglas R. Kern, The Woodlands, TX (US);

Robert J. Schwartz, Houston, TX (US);

Glen King, Rosharon, TX (US);

Kevin Hahn, Missouri City, TX (US);

Malcolm K. Brenner, Bellaire, TX (US);

Assignees:

Baylor College of Medicine, Houston, TX (US);

ADViSYS, Inc., The Woodlands, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A01N 63/00 (2006.01); A01N 65/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 38/24 (2006.01); C07K 1/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention pertains to compositions and methods for plasmid-mediated supplementation. The compositions and method are useful for retarding the growth of the tumor, and retarding cachexia, wasting, anemia and other effects that are commonly associated in cancer bearing animals. Overall, the embodiments of the invention can be accomplished by delivering an effective amount of a nucleic acid expression construct that encodes a GHRH or functional biological equivalent thereof into a tissue of an animal and allowing expression of the encoded. gene in the animal. For example, when such a nucleic acid sequence is delivered into the specific cells of the tissue specific constitutive expression is achieved.


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