The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2007
Filed:
Oct. 19, 2001
David H. Coy, New Orleans, LA (US);
Wojciech J. Rossowski, Kenner, LA (US);
John E. Taylor, Upton, MA (US);
David H. Coy, New Orleans, LA (US);
Wojciech J. Rossowski, Kenner, LA (US);
John E. Taylor, Upton, MA (US);
Societe de Conseils de Recherches et d'Applications Scientifiques, SAS, Paris, FR;
The Administrators of the Tulane Educational Fund, New Orleans, LA (US);
Abstract
The present invention is directed to a novel class of cyclic polypeptides of the formula: (R)-AA-cyclo[AA-AA-AA-AA-AA-Cys]-AA-R, pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification, which inhibit the effects of urotensin-II and are useful for treating a variety of diseases and/or conditions characterized by an excess of urotensin-II including ischaemic heart disease, congestive heart failure, portal hypertension, variceal bleeding, hypotension, angina pectoris, myocardial infarction, ulcers, anxiety, schizophrenia, manic depression, delirium, dementia, mental retardation and/or dyskinesias.