The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2007
Filed:
Mar. 10, 2005
Ernest M. Wright, Los Angeles, CA (US);
Ana Diez-sampedro, Los Angeles, CA (US);
Bruce A. Hirayama, Los Angeles, CA (US);
Hermann Koepsell, Höchberg, DE;
Valentin Gorboulev, Höchberg, DE;
Christina Osswald, Würzburg, DE;
Ernest M. Wright, Los Angeles, CA (US);
Ana Diez-Sampedro, Los Angeles, CA (US);
Bruce A. Hirayama, Los Angeles, CA (US);
Hermann Koepsell, Höchberg, DE;
Valentin Gorboulev, Höchberg, DE;
Christina Osswald, Würzburg, DE;
The Regents of the University of California, Oakland, CA (US);
Abstract
Methods are provided for the modulation of hSGLT3 protein glucosensor activity. The sensor is expressed in cholinergic neurons that regulate muscle activity, and in tissues including the brain and pacreas. The present invention also provides methods of identifying therapeutic compounds that modify the function of these sensors. Such therapeutic compounds have a functional effect on regulators of muscle activity, including gastrointestinal smooth muscles; on regulation of weight and metabolism; regulation of pancreatic function, including glucagons release; and in taste perception.