The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7238673 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 03, 2007

Filed:

Sep. 25, 2001
Applicants:

Elizabeth G. Nabel, Ann Arbor, MI (US);

Gary J. Nabel, Ann Arbor, MI (US);

Inventors:

Elizabeth G. Nabel, Ann Arbor, MI (US);

Gary J. Nabel, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); C12N 15/63 (2006.01); C12N 15/00 (2006.01); C12P 19/34 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for the direct in vivo transformation of cells in and surrounding a solid tumor is disclosed. This method is based on the site-specific delivery of proteins to solid tumors and to tissue surrounding the solid tumor by direct injection of a nucleic acid sequence. In particular, this method is directed to site-specific delivery of nucleic acids encoding major histocompatibility proteins, cytokines, and toxins to a solid tumor. This technique provides for the transfer of vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of disease.


Find Patent Forward Citations

Nabel, Elizabeth. (2007). Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor (U.S. Patent No. 7238673). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7238673

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