The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2007

Filed:

Nov. 19, 2005
Applicants:

Zhigang He, Boston, MA (US);

Qiwei Zhai, Boston, MA (US);

Jing Wang, Boston, MA (US);

Ryan Watts, Stanford, CA (US);

Eric Hoopfer, Stanford, CA (US);

Liqun Luo, Stanford, CA (US);

Inventors:

Zhigang He, Boston, MA (US);

Qiwei Zhai, Boston, MA (US);

Jing Wang, Boston, MA (US);

Ryan Watts, Stanford, CA (US);

Eric Hoopfer, Stanford, CA (US);

Liqun Luo, Stanford, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A01N 43/04 (2006.01); A61K 38/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Reduced degeneration of an axon predetermined to be subject to degenerative neuropathy in a term patient is effected by contacting the axon in situ with an effective amount of a ubiquitin-proteasome system (UPS) inhibitor sufficient to reduce degeneration of the axon; and detecting a resultant reduction in the degeneration of the axon in situ.


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