The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2007
Filed:
Jul. 07, 2004
Takesada Shimura, Saitama, JP;
Satsuki Toriyama, Saitama, JP;
Takesada Shimura, Saitama, JP;
Satsuki Toriyama, Saitama, JP;
Abstract
A cartilage and bone morphogenetic repairing composition which contains a bone morphogenetic protein and a polyoxyethylene-polyoxypropylene glycol is disclosed. It is preferable that the molecular weight of a polyoxypropylene, i.e., a component of said polyoxyethylene-polyoxypropylene glycol, is in the range of about 1,500-4,000 and the weight ratio of ethylene oxide is in the range of 40-80%/molecule, and a concentration of said polyoxyethylene-polyoxypropylene glycol in an aqueous solution is about 10-50%. The composition may be applied in a cartilage and bone morphogenetic method without a surgical operation and comprises a bone morphogenetic protein and a carrier which has a high bio-absorption, a good affinity to the bone morphogenetic protein and is capable of temperature dependent gel-sol reversible transition. The composition may conveniently be applied locally to the site of a bone fracture or bone defect.