The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2007

Filed:

Feb. 20, 2001
Applicants:

Klaus Keplinger, A-6020 Innsbruck, AT;

Martin Wurm, A-6020 Innsbruck, AT;

Gerhard Laus, A-6020 Innsbruck, AT;

Inventors:

Klaus Keplinger, A-6020 Innsbruck, AT;

Martin Wurm, A-6020 Innsbruck, AT;

Gerhard Laus, A-6020 Innsbruck, AT;

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 45/00 (2006.01); A61N 43/16 (2006.01); C07G 5/00 (2006.01); C08L 97/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Endothelial cells have the natural property of releasing soluble factors into the fluid surrounding them, said factors altering the behavior of immune cells. In cell systems containing at least endothelial cells, the release of this type of factor, which promotes the proliferation of resting and weakly activated lymphocytes and at the same time inhibits the proliferation of highly activated lymphocytes and transformed lymphoblasts without impairing their other vital functions, is induced by administration of pentacyclic oxindole alkaloids but inhibited by the concurrent administration of tetracyclic oxindole alkaloids.


Find Patent Forward Citations

Loading…