The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2007
Filed:
Aug. 16, 2005
Benjamin Frydman, Madison, WI (US);
Aldonia L. Valasinas, Madison, WI (US);
Andrei V. Blokhin, Fitchburg, WI (US);
Aparajita Sarkar, Madison, WI (US);
Hirak S. Basu, Madison, WI (US);
Venodhar K. Reddy, Madison, WI (US);
Laurence J. Marton, Palo Alto, CA (US);
Yu Wang, Madison, WI (US);
Benjamin Frydman, Madison, WI (US);
Aldonia L. Valasinas, Madison, WI (US);
Andrei V. Blokhin, Fitchburg, WI (US);
Aparajita Sarkar, Madison, WI (US);
Hirak S. Basu, Madison, WI (US);
Venodhar K. Reddy, Madison, WI (US);
Laurence J. Marton, Palo Alto, CA (US);
Yu Wang, Madison, WI (US);
Other;
Abstract
Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.