The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2007
Filed:
Apr. 26, 2002
Joachim Brendel, Bad Vilbel, DE;
Bernard Pirard, Frankfurt, DE;
Stefan Peukert, Frankfurt, DE;
Heinz-werner Kleemann, Bischofsheim, DE;
Horst Hemmerle, Indianapolis, IN (US);
Joachim Brendel, Bad Vilbel, DE;
Bernard Pirard, Frankfurt, DE;
Stefan Peukert, Frankfurt, DE;
Heinz-Werner Kleemann, Bischofsheim, DE;
Horst Hemmerle, Indianapolis, IN (US);
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention is related to anthranilamides of formula I,in which R(1) to R(7) have the meanings indicated herein, a process for their preparation, their use as medicaments, and pharmaceutical preparations containing them. The compounds act on the Kv1.5 potassium channel and inhibit a potassium current which is referred to as the ultra-rapidly activating delayed rectifier in the atrium of the human heart. The compounds are therefore suitable for use as novel antiarrhythmic agents for the treatment and prophylaxis of atrial arrhythmias (e.g., atrial fibrillation (AF) or atrial flutter).