The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2007
Filed:
Feb. 08, 2005
Joachim Brendel, Bad Vilbel, DE;
Thomas Boehme, Ruesselheim, DE;
Stefan Peukert, Frankfurt, DE;
Heinz-werner Kleemann, Bischofsheim, DE;
Joachim Brendel, Bad Vilbel, DE;
Thomas Boehme, Ruesselheim, DE;
Stefan Peukert, Frankfurt, DE;
Heinz-Werner Kleemann, Bischofsheim, DE;
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
This invention encompasses anthranilamides with heteroarylsulfonyl side chain, process for their preparation, their use as medicament or diagnostic aid, and pharmaceutical preparations containing them. Compounds of formula I, in which R1 to R7 have the meanings stated in the claims, act on the Kv1.5 potassium channel and inhibit a potassium current which is referred to as the ultra-rapidly activating delayed rectifier in the atrium of the human heart. They are therefore suitable as novel antiarrhythmic ingredients, such as for the treatment and prophylaxis of atrial arrhythmias, e.g. atrial fibrillation (AF) or atrial flutter.