The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2007

Filed:

Jan. 13, 2006
Applicants:

Golak Chandra Maikap, Uttar Pradesh, IN;

Deependra Bhatt, Uttar Pradesh, IN;

Bijan Kumar Panda, Uttar Pradesh, IN;

Inventors:

Golak Chandra Maikap, Uttar Pradesh, IN;

Deependra Bhatt, Uttar Pradesh, IN;

Bijan Kumar Panda, Uttar Pradesh, IN;

Assignee:

Dabur Pharma Limited, New Delhi, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 5/04 (2006.01); C07H 5/06 (2006.01); C07H 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a highly stereoselective, simple and economical glycosylation process for preparation of β-anomer enriched 2-deoxy-2,2-D-ribofuranosyl difluoronucleosides of formula (II), and physiologically acceptable slats thereof, in particular, the β-enriched anomer of gemcitabine hydrochloride of formula (IIb) in purity of >99% is provided through utilization of a novel trichloroacetimidate of formula (I).


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