The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2007
Filed:
Oct. 16, 2002
Ruiping Liu, Huntington, NY (US);
Mike DE Vivo, New York, NY (US);
Hans-jurgen Ernst Hess, Old Lyme, CT (US);
Allen Hopper, Glen Rock, NJ (US);
Erik Kuester, Franklin, NJ (US);
Ashok Tehim, Ridgewood, NJ (US);
Ruiping Liu, Huntington, NY (US);
Mike De Vivo, New York, NY (US);
Hans-Jurgen Ernst Hess, Old Lyme, CT (US);
Allen Hopper, Glen Rock, NJ (US);
Erik Kuester, Franklin, NJ (US);
Ashok Tehim, Ridgewood, NJ (US);
Memory Pharmaceuticals Corp., Montvale, NJ (US);
Abstract
Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I:wherein R, R, and Rare as defined herein.