The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2007

Filed:

May. 04, 2005
Applicants:

Russell F. Lang, Pembroke Pines, FL (US);

Dennisse Parra-diaz, Miami, FL (US);

Luisa Oramas, Weston, FL (US);

Barbara Murza, Miami, FL (US);

Susana Maldonado, Miami, FL (US);

Inventors:

Russell F. Lang, Pembroke Pines, FL (US);

Dennisse Parra-Diaz, Miami, FL (US);

Luisa Oramas, Weston, FL (US);

Barbara Murza, Miami, FL (US);

Susana Maldonado, Miami, FL (US);

Assignee:

Beckman Coulter, Inc., Fullerton, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/72 (2006.01); G01N 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and release hemoglobin and a ligand to form a stable chromogen with the hemoglobin. The lytic reagent composition has a pH in a range of 3 to 10. The lytic reagent composition can also include a second quaternary ammonium surfactant. The ligand can be malic acid, malonic acid, ethylene diamine, N,N-diethylethylene diamine, N,N'-diethylethylene diamine, diethylene triamine, tetraethylene pentamine, 1,6-hexanediamine, 1,3-pentanediamine, 2-methylpentamethylenediamine, 1,2-diaminocyclohexane, 4-aminoacetophenone, bis-hexamethylenetriamine, pyridazine, or 3,6-dihyroxypyridazine.


Find Patent Forward Citations

Lang, Russell. (2007). Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement (U.S. Patent No. 7235404). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7235404

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…