The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2007

Filed:

Jul. 18, 2003
Applicants:

Larry C. Mattheakis, Cupertino, CA (US);

Jay Kenneth Trautman, Los Altos, CA (US);

Gregg Peter Solar, San Anselmo, CA (US);

Jinhong Fan, San Mateo, CA (US);

Eugeni Vaisberg, Foster City, CA (US);

Cynthia Lynn Adams, San Carlos, CA (US);

Aibing Rao, Burlingame, CA (US);

Inventors:

Larry C. Mattheakis, Cupertino, CA (US);

Jay Kenneth Trautman, Los Altos, CA (US);

Gregg Peter Solar, San Anselmo, CA (US);

Jinhong Fan, San Mateo, CA (US);

Eugeni Vaisberg, Foster City, CA (US);

Cynthia Lynn Adams, San Carlos, CA (US);

Aibing Rao, Burlingame, CA (US);

Assignee:

Cytokinetics, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 3/00 (2006.01); C12Q 1/68 (2006.01); C12Q 1/26 (2006.01); C12Q 1/04 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.


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