The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2007

Filed:

Nov. 24, 2004
Applicants:

Pamela L. Sharpe, Newark, DE (US);

Qiong Cheng, Wilmington, DE (US);

Melissa D. Bosak, Deptford, NJ (US);

Luan Tao, Claymont, DE (US);

Natalia Sedkova, Cherry Hill, NJ (US);

Inventors:

Pamela L. Sharpe, Newark, DE (US);

Qiong Cheng, Wilmington, DE (US);

Melissa D. Bosak, Deptford, NJ (US);

Luan Tao, Claymont, DE (US);

Natalia Sedkova, Cherry Hill, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 23/00 (2006.01); C07H 21/04 (2006.01); C12N 9/10 (2006.01); C12N 15/74 (2006.01); C12N 1/21 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented Ccarotenoid compounds, and show an increase in the production of Ccarotenoids. The use of the optimized host strains for the production of the Ccarotenoids canthaxanthin and astaxanthin is also described.


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