The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2007

Filed:

Aug. 12, 2002
Applicants:

Lorelie H. Villarete, Alameda, CA (US);

Jackeline Campos, Pittsburg, CA (US);

Wayne LI, Poway, CA (US);

Inventors:

Lorelie H. Villarete, Alameda, CA (US);

Jackeline Campos, Pittsburg, CA (US);

Wayne Li, Poway, CA (US);

Assignee:

Pepgen Corporation, Alameda, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/21 (2006.01); A61K 39/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to hybrid interferon fusion proteins formed of an interferon-α protein where the C-terminal region of the interferon-α protein is replaced by a C-terminal region of interferon-τ. Also described are nucleic acid sequences encoding the interferon fusion proteins, expression vectors containing such sequences, and therapeutic applications of the interferon fusion proteins. The therapeutic applications include antiviral, anticellular proliferation, and anti-inflammatory applications. One advantage of the interferon fusion polypeptides of the present invention is that they have lower cytotoxic side effects when used to treat cells.


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