The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2007
Filed:
Oct. 14, 2003
Raghavan Rajagopalan, Solon, OH (US);
Samuel I. Achilefu, St. Louis, MO (US);
Joseph E. Bugaj, St. Charles, MO (US);
Richard B. Dorshow, St. Louis, MO (US);
Muthunadar P. Periasamy, Chesterfield, MO (US);
Raghavan Rajagopalan, Solon, OH (US);
Samuel I. Achilefu, St. Louis, MO (US);
Joseph E. Bugaj, St. Charles, MO (US);
Richard B. Dorshow, St. Louis, MO (US);
Muthunadar P. Periasamy, Chesterfield, MO (US);
Mallinckrodt, Inc., St. Louis, MO (US);
Abstract
The invention discloses compounds and compositions for dual phototherapy and combined therapy and diagnosis of tumors and other lesions. The compounds have a Dye that, when photoactivated, operates via Type I and/or Type II mechanisms. Other Dye or azide components may operate by the same or different mechanisms. Selection of particular components in a compound, and formulation of the compound(s) in a composition permit different activation wavelengths to be used for different therapies. A targeting moiety may be added to the compound or composition so that the Dye locates at a particular site, such as a hormone-sensitive tumor, for diagnosis and/or treatment. The compounds and compositions may be incorporated within liposomes.