The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2007
Filed:
May. 07, 2001
Applicant:
Lars Baltzer, Göteborg, SE;
Inventor:
Lars Baltzer, Göteborg, SE;
Assignee:
Modpro AB, Göteborg, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for site-selective acyl transfer in amidation of folded polypeptides and proteins based on the use of a chemical structure element comprising an imidazole function, such as histidine, in position i flanked by at least one functional group to be amidated, such as lysinc, in position i+3+4k. where K is an integer equal to or higher than −1, or in position i−4−4n, wherein n is an integer equal to or higher than 0, and at least one activating group, such as serine, in position i+4+4n or i−3−4n, respectively.