The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2007

Filed:

Jan. 28, 2003
Applicants:

Hiroaki Shiohara, Yamagata-mura, JP;

Tetsuya Nakamura, Toyoshina-machi, JP;

Norihiko Kikuchi, Matsumoto, JP;

Tomonaga Ozawa, Matsumoto, JP;

Makio Kitazawa, Matsumoto, JP;

Inventors:

Hiroaki Shiohara, Yamagata-mura, JP;

Tetsuya Nakamura, Toyoshina-machi, JP;

Norihiko Kikuchi, Matsumoto, JP;

Tomonaga Ozawa, Matsumoto, JP;

Makio Kitazawa, Matsumoto, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/19 (2006.01); C07C 303/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound represented by general formula (I): or pharmaceutically acceptable salts thereof, wherein W is O, S(O), CHand the like; Ris halogen, lower alkyl, halo-lower alkyl, CN and the like; Ris hydrogen and the like; Ris hydrogen, halogen, alkyl, halo-lower alkyl, substituted alkyl, aryl, aralkyl, alkoxy, substituted alkoxy, alkanoyl, aroyl, —CONR(R), —S(O)R, —SONR(R) and the like; Ris hydrogen, halogen, alkyl, substituted alkyl and the like; A is —N(R)CO—A—CORand the like; pharmaceutical compositions containing them and their uses, which have a high affinity to human thyroid hormone receptors, in particular human thyroid hormone receptor β.


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