The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2007
Filed:
Jul. 21, 2005
Zhenkun MA, Dallas, TX (US);
Jing LI, Dallas, TX (US);
Susan Harran, Dallas, TX (US);
Yong He, Arlington, TX (US);
Keith P. Minor, Dallas, TX (US);
IN Ho Kim, Lewisville, TX (US);
Charles Z. Ding, Plano, TX (US);
Jamie C. Longgood, Carrolton, TX (US);
Yafei Jin, Dallas, TX (US);
Keith D. Combrink, Fort Worth, TX (US);
Zhenkun Ma, Dallas, TX (US);
Jing Li, Dallas, TX (US);
Susan Harran, Dallas, TX (US);
Yong He, Arlington, TX (US);
Keith P. Minor, Dallas, TX (US);
In Ho Kim, Lewisville, TX (US);
Charles Z. Ding, Plano, TX (US);
Jamie C. Longgood, Carrolton, TX (US);
Yafei Jin, Dallas, TX (US);
Keith D. Combrink, Fort Worth, TX (US);
Cumbre Pharmaceuticals Inc., Dallas, TX (US);
Abstract
Novel rifamycin derivatives of formula I (both hydroquinone and corresponding quinone (C-C) forms): or their salts, hydrates or prodrugs thereof,wherein: a preferred R comprises hydrogen, acetyl; L is a linker, a preferred linker group elements selected from any combination of 1 to 5 groups shown FIG., provided L is not wherein Ris H, methyl or alkyl. The inventive compounds exhibit valuable antibiotic properties. Formulations having these compounds can be used in the control or prevention of infectious diseases in mammals, both humans and non-humans. In particular, the compounds exhibit a pronounced antibacterial activity, even against multiresistant strains of microbes.