The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2007

Filed:

Sep. 25, 2003
Applicants:

Kenneth W. Dobie, Del Mar, CA (US);

Sanjay Bhanot, Encinitas, CA (US);

Murielle Veniant-ellison, Thousand Oaks, CA (US);

Richard A. Lindberg, Thousand Oaks, CA (US);

John R. Shutter, Moorpark, CA (US);

Inventors:

Kenneth W. Dobie, Del Mar, CA (US);

Sanjay Bhanot, Encinitas, CA (US);

Murielle Veniant-Ellison, Thousand Oaks, CA (US);

Richard A. Lindberg, Thousand Oaks, CA (US);

John R. Shutter, Moorpark, CA (US);

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); A16K 48/00 (2006.01); C12Q 1/68 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antisense compounds, compositions and methods are provided for modulating the expression of forkhead box O1A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding forkhead box O1A. Methods of using these compounds for modulation of forkhead box O1A expression and for treatment of diseases associated with expression of forkhead box O1A are provided, in particular, for methods of treating diabetes.


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