The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2007
Filed:
Nov. 05, 2001
Applicants:
Stephanie C. Pero, Essex Junction, VT (US);
David N. Krag, Shelburne, VT (US);
Lyn Oligino, South Burlington, VT (US);
Inventors:
Stephanie C. Pero, Essex Junction, VT (US);
David N. Krag, Shelburne, VT (US);
Lyn Oligino, South Burlington, VT (US);
Assignee:
University of Vermont and State Agricultural College, Burlington, VT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides methods and compositions for treating subjects using Grb7 antagonists. Specifically disclosed are Grb7 antagonists that bind selectively to Grb7 and interfere with the ability of Grb7 to bind to its native ligands. These compositions are useful in the prevention and treatment of disorders characterized by abnormal interaction of Grb7 with its native ligands (e.g., ErbB2).