The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2007

Filed:

Aug. 03, 2001
Applicants:

Manoj Kumar, Fremont, CA (US);

Fernando Valle, Burlingame, CA (US);

Veronique A. Dartois, San Diego, CA (US);

James A. Hoch, La Jolla, CA (US);

Inventors:

Manoj Kumar, Fremont, CA (US);

Fernando Valle, Burlingame, CA (US);

Veronique A. Dartois, San Diego, CA (US);

James A. Hoch, La Jolla, CA (US);

Assignees:

Genencor International, Inc., Palo Alto, CA (US);

E.P.I. Liquidation Co., La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12P 7/40 (2006.01); C12P 21/06 (2006.01); C12Q 1/26 (2006.01); C07K 14/00 (2006.01); C12P 19/34 (2006.01); C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides isolated nucleic acid molecules encoding polypeptides having 2,5-DKG permease activity, and oligonucleotides therefrom. The isolated nucleic acid molecules can be expressed in appropriate bacterial cells to enhance the production of 2-KLG, which can subsequently be converted to ascorbic acid. Further provided are isolated polypeptides having 2,5-DKG permease acitivity, immunogenic peptides therefrom, and antibodies specific therefor. The invention also provides methods of identifying novel 2,5-DKG permeases.


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