The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2007
Filed:
Dec. 30, 2003
Clark A. Briggs, Libertyville, IL (US);
Murali Gopalakrishnan, Grayslake, IL (US);
David G. MC Kenna, McHenry, IL (US);
Lisa M. Monteggia, Lindenhurst, IL (US);
Jean-marc Roch, Waukegan, IL (US);
James P. Sullivan, Deerfield, IL (US);
Edward Touma, North Chicago, IL (US);
Clark A. Briggs, Libertyville, IL (US);
Murali Gopalakrishnan, Grayslake, IL (US);
David G. Mc Kenna, McHenry, IL (US);
Lisa M. Monteggia, Lindenhurst, IL (US);
Jean-Marc Roch, Waukegan, IL (US);
James P. Sullivan, Deerfield, IL (US);
Edward Touma, North Chicago, IL (US);
Abbott Laboratories, Abbott Park, IL (US);
Abstract
A variant human α7 nicotinic acetylcholine receptor (nAChR) polypeptide is provided wherein the variant contains an amino acid substitution at the valine-274 position of the wild-type human α7 nAChR. Nucleic acid molecules encoding the variant human α7 nAChR, vectors and host cells containing such nucleic acid molecules are also provided. In addition, methods are provided for producing the variant as are methods of using such variants for screening compounds for activity at the nAChR.