The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2007
Filed:
Nov. 27, 2002
Ian Hector Frazer, St. Lucia, AU;
Jian Zhou, Deceased, Jindalee, AU;
Xiao Yi Sun, Legal Representative, by Jindalee, AU;
Ian Hector Frazer, St. Lucia, AU;
Jian Zhou, deceased, Jindalee, AU;
Xiao Yi Sun, legal representative, by Jindalee, AU;
The University of Queensland, St. Lucia, Queensland, AU;
Abstract
A method of constructing a synthetic polynucleotide, the method including selecting a first codon of a parent polynucleotide that encodes a polypeptide for replacement with a synonymous codon, wherein the synonymous codon is selected on the basis that it exhibits a higher translational efficiency in an epithelial cell of a mammal than the first codon in a comparison of translational efficiencies of codons in test cells of the same type as the epithelial cell; and replacing the first codon with the synonymous codon to construct the synthetic polynucleotide.