The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2007

Filed:

Jul. 11, 2003
Applicants:

Akio Matsuda, Shizuoka, JP;

Goichi Honda, Shizuoka, JP;

Shuji Muramatsu, Shizuoka, JP;

Yukiko Nagano, Shizuoka, JP;

Inventors:

Akio Matsuda, Shizuoka, JP;

Goichi Honda, Shizuoka, JP;

Shuji Muramatsu, Shizuoka, JP;

Yukiko Nagano, Shizuoka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C12Q 1/68 (2006.01); A01N 43/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are proteins having NF-κB activity, which are used for diagnosing, treating or preventing diseases associated with the excessive activation or inhibition of NF-κB. Using plasmid pNFκB-Luc, cDNA encoding a protein capable of activating NF-κB has been cloned from a cDNA library constructed from human lung fibroblasts, and the DNA sequence and the deduced amino acid sequence determined. The protein, the DNA encoding the protein, a recombinant vector containing the DNA, and a transformant containing the recombinant vector are useful for screening a substance inhibiting or promoting NF-κB activation.


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