The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2007

Filed:

Jun. 02, 2005
Applicants:

Junming Le, Jackson Heights, NY (US);

Jan Vilcek, New York, NY (US);

Peter Daddona, Palo Alto, CA (US);

John Ghrayeb, Thorndale, PA (US);

David M. Knight, Berwyn, PA (US);

Scott A. Siegel, Westborough, MA (US);

Inventors:

Junming Le, Jackson Heights, NY (US);

Jan Vilcek, New York, NY (US);

Peter Daddona, Palo Alto, CA (US);

John Ghrayeb, Thorndale, PA (US);

David M. Knight, Berwyn, PA (US);

Scott A. Siegel, Westborough, MA (US);

Assignees:

New York University, New York, NY (US);

Centocor, Inc., Malvern, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Anti-TNF antibodies and anti-TNF peptides, specific for tumor necrosis factor (TNF) are useful for in vivo diagnosis and therapy of a number of TNF-mediated pathologies and conditions, as well as polynucleotides coding for anti-TNF murine and chimeric antibodies, peptides, methods of making and using the antibody or peptides in immunoassays and immuno-therapeutic approaches are provided, where the anti-TNF peptide is selected from a soluble portion of TNF receptor, an anti-TNF antibody or structural analog thereof.


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