The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2007
Filed:
Jul. 21, 2005
Charles Z. Ding, Plano, TX (US);
Zhenkun MA, Dallas, TX (US);
Jing LI, Dallas, TX (US);
Susan Harran, Dallas, TX (US);
Yong He, Arlington, TX (US);
Keith P. Minor, Dallas, TX (US);
IN Ho Kim, Lewisville, TX (US);
Jamie C. Longgood, Carrollton, TX (US);
Yafei Jin, Dallas, TX (US);
Keith D. Combrink, Fort Worth, TX (US);
Charles Z. Ding, Plano, TX (US);
Zhenkun Ma, Dallas, TX (US);
Jing Li, Dallas, TX (US);
Susan Harran, Dallas, TX (US);
Yong He, Arlington, TX (US);
Keith P. Minor, Dallas, TX (US);
In Ho Kim, Lewisville, TX (US);
Jamie C. Longgood, Carrollton, TX (US);
Yafei Jin, Dallas, TX (US);
Keith D. Combrink, Fort Worth, TX (US);
Cumbre Pharmaceuticals Inc., Dallas, TX (US);
Abstract
Rifamycin derivatives having the following structure of general formula I (both hydroquinone and corresponding quinone (C-C) forms): or its salts, hydrates or prodrugs thereof; wherein a preferred Rcomprises hydrogen or acetyl and a prefered Rcomprises hydrogen, methyl or other lower alkyls; wherein asterik (*) denotes the carbon bearing the chiral center, wherein absolute configuration is assigned as R or S. Methods of preparation of the aforementioned rifamycin derivatives are also described. The compounds exhibit antimicrobial activities, including activities against drug-resistant microorganisms.