The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2007
Filed:
Jul. 27, 2005
Gary B. Schneider, Hudson, OH (US);
Steven N. Popoff, Warrington, PA (US);
Fayez Safadi, Philadelphia, PA (US);
Gary B. Schneider, Hudson, OH (US);
Steven N. Popoff, Warrington, PA (US);
Fayez Safadi, Philadelphia, PA (US);
Northeastern Ohio Universities College of Medicine, Rootstown, OH (US);
Temple University, Philadelphia, PA (US);
Abstract
Agents for promoting bone deposition and growth in a mammalian subject. The agents are O-glycosylated and non-glycosylated peptides that are derived from vitamin D binding protein, collectively referred to hereinafter as 'DBP' peptides. The DBP peptides are from 3 to 18, preferably from 4 to 14 amino acids in length and comprise a sequence which is at least 80% identical, preferably at least 90% identical to the amino acid sequence of a fragment contained within domain III of DBP. Methods for promoting bone deposition in a subject in need of the same are also provided. The methods comprise administering to the subject a therapeutically effective quantity of an agent selected from the group consisting of an activated form of vitamin D binding protein referred to hereinafter as 'ADBP', one or more DBP peptides, and combinations thereof. The agents may be administered locally or systemically.