The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2007

Filed:

Mar. 12, 2001
Applicants:

Bridget Kathleen Mapleson, Liverpool, GB;

Philip Sizer, Helsby, GB;

Inventors:

Bridget Kathleen Mapleson, Liverpool, GB;

Philip Sizer, Helsby, GB;

Assignee:

Medeva Europe Limited, London, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of removing bacterial endotoxin from a pharmaceutical process solution is disclosed. In one embodiment, the method comprises treating the solution with a surfactant effective to dissociate the endotoxin from a pharmaceutical drug or vaccine substance in the solution, and then filtering the solution through a molecular cut-off filter having a pore size effective to retain the pharmaceutical drug or vaccine substance but allow the dissociated bacterial endotoxin to pass therethrough.


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