The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2007
Filed:
Oct. 31, 2005
Christophe Ripoll, Saint-Andre, FR;
Barbara Schmidt, Somerset, NJ (US);
Nebojsa Ilic, Highland Park, NJ (US);
Ilya Raskin, Manalapan, NJ (US);
Christophe Ripoll, Saint-Andre, FR;
Barbara Schmidt, Somerset, NJ (US);
Nebojsa Ilic, Highland Park, NJ (US);
Ilya Raskin, Manalapan, NJ (US);
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
Abstract
A method of preparing a chicory extract enriched with sesquiterpene lactones is provided. The method includes performing an initial extraction chicory in a polar solvent, such as methanol or ethanol, at ambient temperature to form an alcoholic extract. The alcoholic extract is subsequently defatted with a non-polar solvent, preferably hexane or n-heptane. A second extraction of the defatted alcoholic extract is performed with a solvent which is more polar than the solvent used in the defatting process and less polar than the solvent used in the initial extraction, for example, it can be chosen from the group consisting of ethyl acetate, n-butanol, isopropanol, n-propanol, dichloromethane, acetonitrile, and mixtures thereof; resulting in a sesquiterpene lactones enriched extract, preferably containing at least 60% sesquiterpene lactones.