The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2007
Filed:
Jun. 07, 1995
Conjugate between a modified superantigen and a target-seeking compound and the use of the conjugate
Applicants:
Lars Abrahmsen, Bromma, SE;
Per Bjork, Helsingborg, SE;
Mikael Dohlsten, Lund, SE;
Terje Kalland, Arese, IT;
Inventors:
Lars Abrahmsen, Bromma, SE;
Per Bjork, Helsingborg, SE;
Mikael Dohlsten, Lund, SE;
Terje Kalland, Arese, IT;
Assignee:
Active Biotech AB, Lund, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07K 19/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for the treatment of a disease in a mammal by administering a therapeutically effective amount of a conjugate comprising a biospecific affinity counterpart and a peptide, wherein the peptide contains an amino acid sequence that is derived from staphylococcal enterotoxin A, binds to a Vβ of a T cell receptor, and has a D227A mutation so that the peptide has a modified ability to bind to MHC class II antigens.