The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2007

Filed:

Jun. 28, 2004
Applicants:

Roberto Weinmann, Lawrenceville, NJ (US);

Howard M. Einspahr, Lawrenceville, NJ (US);

Stanley R. Krystek, Ringoes, NJ (US);

John S. Sack, Lawrenceville, NJ (US);

Mark E. Salvati, Lawrenceville, NJ (US);

John S. Tokarski, Princeton, NJ (US);

Ricardo M. Attar, Lawrenceville, NJ (US);

Chihuei Wang, Plainsboro, NJ (US);

Inventors:

Roberto Weinmann, Lawrenceville, NJ (US);

Howard M. Einspahr, Lawrenceville, NJ (US);

Stanley R. Krystek, Ringoes, NJ (US);

John S. Sack, Lawrenceville, NJ (US);

Mark E. Salvati, Lawrenceville, NJ (US);

John S. Tokarski, Princeton, NJ (US);

Ricardo M. Attar, Lawrenceville, NJ (US);

Chihuei Wang, Plainsboro, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G06F 19/00 (2006.01); C07K 1/00 (2006.01); C07J 1/00 (2006.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

The first crystal structure of the androgen receptor ligand binding domain has been determined to 2.0 angstrom resolution. Disclosed are the coordinates for the crystal structure, and methods for determining agonists, partial agonists, antagonists, partial antagonists and selective androgen receptors modulators (SARMs) of the androgen receptor.


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