The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2007
Filed:
Dec. 15, 2005
Yong Seo Cho, Seoul, KR;
Joo Hwan Cha, Seoul, KR;
AE Nim Pae, Seoul, KR;
Hun Yeong Koh, Seoul, KR;
Chul Shin, Incheon, KR;
Yong Seo Cho, Seoul, KR;
Joo Hwan Cha, Seoul, KR;
Ae Nim Pae, Seoul, KR;
Hun Yeong Koh, Seoul, KR;
Chul Shin, Incheon, KR;
Korea Institute of Science and Technology, Seoul, KR;
Abstract
The present invention relates to bicyclic tetrahydrofuran lactone derivatives of Formula (1) and a preparation method thereof, and particularly it relates to a process of preparing compounds of Formula (1) by performing an intramolecular cyclization of tetrahydrofuran-allenic acid derivatives in the presence of a phenyl halide, a palladium catalyst and a base: wherein n is 1 or 2, and R is phenyl optionally substituted with C–Calkyl, C–Calkoxy, hydroxyl or C–Chydroxyalkyl group.