The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2007
Filed:
May. 22, 2002
GE Ping, Durham, CT (US);
Taeyoung Yoon, Guilford, CT (US);
LU Yan Zhang, Branford, CT (US);
Raymond F. Horvath, Guilford, CT (US);
Ge Ping, Durham, CT (US);
Taeyoung Yoon, Guilford, CT (US);
Lu Yan Zhang, Branford, CT (US);
Raymond F. Horvath, Guilford, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Novel 5-substituted-2-arylpyridine compounds are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyridine compounds provided herein are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds provided are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.