The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2007

Filed:

Nov. 30, 2005
Applicants:

Mark D. Wittman, Waliingford, CT (US);

Neelakantan Balasubramanian, Madison, CT (US);

Upender Velaparthi, North Haven, CT (US);

Kurt Zimmermann, Durham, CT (US);

Mark G. Saulnier, Higgannum, CT (US);

Peiying Liu, Madison, CT (US);

Xiaopeng Sang, Glastonbury, CT (US);

David B. Frennesson, Nauatuck, CT (US);

Karen M. Stoffan, Hartford, CT (US);

James G. Tarrant, Hamden, CT (US);

Anne Marinier, Kirkland, CA;

Stephan Roy, St-Lambert, CA;

Inventors:

Mark D. Wittman, Waliingford, CT (US);

Neelakantan Balasubramanian, Madison, CT (US);

Upender Velaparthi, North Haven, CT (US);

Kurt Zimmermann, Durham, CT (US);

Mark G. Saulnier, Higgannum, CT (US);

Peiying Liu, Madison, CT (US);

Xiaopeng Sang, Glastonbury, CT (US);

David B. Frennesson, Nauatuck, CT (US);

Karen M. Stoffan, Hartford, CT (US);

James G. Tarrant, Hamden, CT (US);

Anne Marinier, Kirkland, CA;

Stephan Roy, St-Lambert, CA;

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 413/14 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inhibiting tyrosine kinase enzymes.


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