The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2007
Filed:
Aug. 12, 2004
Applicants:
Sankar Chatterjee, Wynnewood, PA (US);
Mohamed Iqbal, Malvern, PA (US);
Ernesto Menta, Cernusco sul Naviglio, IT;
Ambrogio Oliva, Saronno, IT;
Inventors:
Sankar Chatterjee, Wynnewood, PA (US);
Mohamed Iqbal, Malvern, PA (US);
Ernesto Menta, Cernusco sul Naviglio, IT;
Ambrogio Oliva, Saronno, IT;
Assignee:
Cephalon, Inc., Frazer, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); C07F 5/04 (2006.01); A61K 31/69 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.