The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2007
Filed:
Feb. 19, 2003
Robert Van Der Geize, Veendam, NL;
Peter Van Der Meijden, Oss, NL;
Gerda Hessels, Groningen, NL;
Lubbert Dijkhuizen, Zuidlaren, NL;
Robert Van Der Geize, Veendam, NL;
Peter Van Der Meijden, Oss, NL;
Gerda Hessels, Groningen, NL;
Lubbert Dijkhuizen, Zuidlaren, NL;
N.V. Organon, Oss, NL;
Abstract
The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499–1695 of SEQ ID NO: 1 or by nucleotides 387–1427 of SEQ ID NO:2, respectively, and functional homologues thereof. The polynucleotides of the invention can be used to construct genetically modified microorganisms blocked in 3-ketosteroid 9α-hydroxylase activity, which are useful in the microbial degradation of steroids to accumulate certain steroid products.