The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2007
Filed:
Jul. 10, 2001
Michael Econs, Indianapolis, IN (US);
Ken White, Carmel, IN (US);
Tim Matthias Strom, Munich, DE;
Thomas Meitinger, Munich, DE;
Michael Econs, Indianapolis, IN (US);
Ken White, Carmel, IN (US);
Tim Matthias Strom, Munich, DE;
Thomas Meitinger, Munich, DE;
Advanced Research and Technology Institute, Indianapolis, IN (US);
Ludwig-Maximilians-Universitat Muchen, Munich, DE;
Abstract
The invention relates to novel nucleic acids encoding a fibroblast growth factor-23(FGF23) and proteins encoded thereby, mutations in which are associated with autosomal dominant rickets (ADHR). The invention further relates to methods of diagnosing and treating hypophosphatemic and hyperphosphatemic disorders comprising inhibiting or stimulating, respectively, the biological activity of FGF23 in a patient. The invention also relates to methods of treating osteoporosis, dermatomyositis, and coronary artery disease comprising stimulating the biological activity of FGF23 in a patient.