The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2007

Filed:

Oct. 08, 1999
Applicants:

Pengbo Zhou, New York, NY (US);

Peter M. Howley, Wellesley, MA (US);

Inventors:

Pengbo Zhou, New York, NY (US);

Peter M. Howley, Wellesley, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 9/00 (2006.01); C12N 5/16 (2006.01); C12N 5/18 (2006.01); C12N 5/22 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods and reagents for targeting proteolysis of a polypeptide by cis or trans association with a ubiquitin protein ligase, and further provides methods and reagents for inhibiting the ubiquitination and proteolysis of cellular proteins which are recognized by a ubiquitin protein ligase.


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