The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2007
Filed:
Aug. 16, 2004
Dennis P. Curran, Pittsburgh, PA (US);
Bom David, Pittsburgh, PA (US);
Thomas G. Burke, Lexington, KY (US);
Dennis P. Curran, Pittsburgh, PA (US);
Bom David, Pittsburgh, PA (US);
Thomas G. Burke, Lexington, KY (US);
University of Pittsburgh, Pittsburgh, PA (US);
Abstract
A compound has the formula in racemic form, enantiomerically enriched form or enantiomerically pure form. Ris preferably —Si(RRR) or —(R)Si(RRR), wherein Ris an alkylene group, an alkenylene group, or an alkynylene group; and R, Rand Rare independently a Calkyl group, a Calkenyl group, a Calkynyl group, an aryl group or a —(CH)Rgroup, wherein N is an integer within the range of 1 through 10 and Ris a hydroxy group, alkoxy group, an amino group, an alkylamino group, a dialkylamino group, a halogen atom, a cyano group, —SRor a nitro group. Rcan be broadly substituted. Ris preferably a Calkyl group, an alkenyl group, an alkynyl group, or a benzyl group. Ris preferably H, F or —CH. Ris Ris —C(O)Ror H. The E-ring (the lactone ring) may be opened. A method of synthesis of compound (1) and intermediates in the synthesis thereof are provided.