The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2007
Filed:
Aug. 28, 2000
Hans-georg Lerchen, Leverkusen, DE;
Jörg Baumgarten, Wuppertal, DE;
Ulf Brüggemeier, Leichlingen, DE;
Markus Albers, Leverkusen, DE;
Andreas Schoop, Vienna, AT;
Thomas-j. Schulze, Thousand Oaks, CA (US);
Hans-Georg Lerchen, Leverkusen, DE;
Jörg Baumgarten, Wuppertal, DE;
Ulf Brüggemeier, Leichlingen, DE;
Markus Albers, Leverkusen, DE;
Andreas Schoop, Vienna, AT;
Thomas-J. Schulze, Thousand Oaks, CA (US);
Bayer Aktiengesellschaft, Leverkusen, DE;
Abstract
The present invention relates to cytostatics which have a tumour-specific action as a result of linkage to αβintegrin antagonists via preferred linking units. The preferred linking units guarantee serum stability of the conjugate of cytostatic and αβintegrin antagonist and at the same time the desired intracellular action in tumour cells as a result of their enzymatic or hydrolytic cleavability with release of the cytostatic.