The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2007

Filed:

Dec. 10, 2001
Applicants:

Frank Himmelsbach, Mittelbiberach, DE;

Elke Langkopf, Warthausen, DE;

Thomas Metz, Vienna, AT;

Flavio Solca, Vienna, AT;

Birgit Jung, Schwabenheim, DE;

Anke Baum, Vienna, AT;

Inventors:

Frank Himmelsbach, Mittelbiberach, DE;

Elke Langkopf, Warthausen, DE;

Thomas Metz, Vienna, AT;

Flavio Solca, Vienna, AT;

Birgit Jung, Schwabenheim, DE;

Anke Baum, Vienna, AT;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 31/47 (2006.01); C07D 239/72 (2006.01); C07D 215/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to bicyclic heterocycles of general formula wherein Rto R, A to E and X are defined as in claim 1, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, in particular an inhibitory effect on signal transduction mediated by tyrosine kinases, their use in the treatment of diseases, especially tumoral diseases and diseases of the lungs and airways, and the preparation thereof.


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