The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2007
Filed:
Nov. 26, 2001
Georgy Nikolaevich Vorozhtsov, Moscow, RU;
Eduard Izrailevich Galperin, Moscow, RU;
Roman Sergeevich Goloschapov, Moscow, RU;
Sergei Vitalievich Grachev, Moscow, RU;
Tatyana Gennadievna Dyuzheva, Pavshino, RU;
Natalya Ivanovna Kazachkina, Moskovskaya oblast, RU;
Oleg Leonidovich Kalia, Moscow, RU;
Yury Mikhailovich Luzhkov, Moscow, RU;
Evgeny Antonovich Lukyanets, Moscow, RU;
Vadim Romanovich Nakhamiyaev, Moscow, RU;
Georgy Nikolaevich Vorozhtsov, Moscow, RU;
Eduard Izrailevich Galperin, Moscow, RU;
Roman Sergeevich Goloschapov, Moscow, RU;
Sergei Vitalievich Grachev, Moscow, RU;
Tatyana Gennadievna Dyuzheva, Pavshino, RU;
Natalya Ivanovna Kazachkina, Moskovskaya oblast, RU;
Oleg Leonidovich Kalia, Moscow, RU;
Yury Mikhailovich Luzhkov, Moscow, RU;
Evgeny Antonovich Lukyanets, Moscow, RU;
Vadim Romanovich Nakhamiyaev, Moscow, RU;
Abstract
A method for regional administration of preparations during the therapy of liver tumor, comprising administering a preparation into a branch of the portal vein with the simultaneous occlusion of afferent and efferent lobe vessels (branches of the portal vein proximal the place of puncture, branches of the hepatic artery and lobar hepatic vein) for 5–15 minutes. During catalytic therapy, it is preferable to use Teraphtalum as the preparation and to administer ascorbic acid after termination of occlusion. During photodynamic therapy, it is preferable to use photosens as the preparation and to carry out irradiation of the tumor after 10–35 minutes. This method of administration provides for the predominant accumulation of the preparations in the target lobe (tumor carrier lobe) of the liver, their low penetration into the systemic blood flow, which makes it possible to reduce the dose of the preparation and its general toxicity.