The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2007

Filed:

Nov. 20, 2002
Applicants:

Thomas T. Andersen, Albany, NY (US);

James A. Bennett, Delmar, NY (US);

Herbert I. Jacobson, Albany, NY (US);

Fassil B. Mesfin, Albany, NY (US);

Inventors:

Thomas T. Andersen, Albany, NY (US);

James A. Bennett, Delmar, NY (US);

Herbert I. Jacobson, Albany, NY (US);

Fassil B. Mesfin, Albany, NY (US);

Assignee:

Ordway Research Institute, Inc., Clifton Park, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 5/055 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides diagnostic procedures wherein the presence or absence of a cell-proliferating disorder, e.g., a breast cancer, may be determined. The imaging agents of the invention include alpha-fetoprotein hydrophilic analogs which have been determined to target cancers, e.g., breast cancer, and are also anti-cell proliferating in nature. These modulators contain amino acid structures which are arranged as a hydrophilic analog of an alpha-fetoprotein. The modulator may be a peptide; a peptidomimetic; or may be in the form of a pharmaceutically acceptable scaffold, such as a polycyclic hydrocarbon to which is attached the necessary amino acid structures. The imaging agents of the invention further comprise an imaging moiety that allows for the imaging of the area targeted by the imaging agent.


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