The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2007
Filed:
Apr. 10, 2000
Richard D. Hull, Colts Neck, NJ (US);
Eugene M. Fluder, Jr., Hamilton Square, NJ (US);
Suresh B. Singh, Kendall Park, NJ (US);
Robert P. Sheridan, Bloomfield, NJ (US);
Robert B. Nachbar, Washington Crossing, NJ (US);
Simon K. Kearsley, Westfield, NJ (US);
Richard D. Hull, Colts Neck, NJ (US);
Eugene M. Fluder, Jr., Hamilton Square, NJ (US);
Suresh B. Singh, Kendall Park, NJ (US);
Robert P. Sheridan, Bloomfield, NJ (US);
Robert B. Nachbar, Washington Crossing, NJ (US);
Simon K. Kearsley, Westfield, NJ (US);
Axontologic, Inc., Orlando, FL (US);
Abstract
A novel extension of the vector space model for computing chemical similarity is described. In one embodiment, a method calculates similarity between molecules and molecular descriptors using the singular value composition (SVD) of a molecule/descriptor matrix and, for example, an identity matrix, to create a low dimensional representation of the original descriptor space. Probe or query molecules then can be projected into the low dimensional representation and compared to the molecules from the original matrix.