The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2007
Filed:
Apr. 02, 2004
Sherin S. Abdel-meguid, Exton, PA (US);
Robert E. Babine, Franklin, MA (US);
Hongfeng Deng, Acton, MA (US);
Lei Jin, Wellesley, MA (US);
Jian Lin, Walpole, MA (US);
Scott R. Magee, Somerville, MA (US);
Harold V. Meyers, Weston, MA (US);
Pramod Pandey, Canton, MA (US);
Michael J. Rynkiewicz, Boston, MA (US);
David T. Weaver, Newton, MA (US);
Zihong Gho, Southbury, CT (US);
Thomas D. Bannister, Northborough, MA (US);
Sherin S. Abdel-Meguid, Exton, PA (US);
Robert E. Babine, Franklin, MA (US);
Hongfeng Deng, Acton, MA (US);
Lei Jin, Wellesley, MA (US);
Jian Lin, Walpole, MA (US);
Scott R. Magee, Somerville, MA (US);
Harold V. Meyers, Weston, MA (US);
Pramod Pandey, Canton, MA (US);
Michael J. Rynkiewicz, Boston, MA (US);
David T. Weaver, Newton, MA (US);
Zihong Gho, Southbury, CT (US);
Thomas D. Bannister, Northborough, MA (US);
Daiamed, Inc., Cambridge, MA (US);
Abstract
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.