The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2007
Filed:
Jul. 24, 2003
Kenneth H. Eckels, Rockville, MD (US);
Joseph B. Putnak, Silver Spring, MD (US);
Doria R. Dubois, Wheaton, MD (US);
Bruce L. Innis, Haverford, PA (US);
Charles H. Hoke, Columbia, MD (US);
Wellington Sun, Rockville, MD (US);
Niranjan Kanesa-thasan, Rockville, MD (US);
Kenneth H. Eckels, Rockville, MD (US);
Joseph B. Putnak, Silver Spring, MD (US);
Doria R. Dubois, Wheaton, MD (US);
Bruce L. Innis, Haverford, PA (US);
Charles H. Hoke, Columbia, MD (US);
Wellington Sun, Rockville, MD (US);
Niranjan Kanesa-Thasan, Rockville, MD (US);
United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
The present invention provides vaccine compositions of attenuated dengue virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against all four dengue virus serotypes by administration of attenuated dengue-1, dengue-2, dengue-3, and dengue-4 virus.