The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7214820 B1

PDF
Full Text
Expired
Date of Patent:
May. 08, 2007

Filed:

Jan. 20, 2004
Applicants:

Shunji Kamiyama, Kobe, JP;

Kazuto Yoshida, Ibo-gun, JP;

Yasuo Chikusa, Himeji, JP;

Jun Matsumoto, Kakogawa, JP;

Keisuke Matsuyama, Kobe, JP;

Inventors:

Shunji Kamiyama, Kobe, JP;

Kazuto Yoshida, Ibo-gun, JP;

Yasuo Chikusa, Himeji, JP;

Jun Matsumoto, Kakogawa, JP;

Keisuke Matsuyama, Kobe, JP;

Assignee:

Nagase & Co., Ltd., Osaka-shi, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07B 57/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method for producing optically active flurbiprofen. The method of the present invention includes mixing racemic flurbiprofen and (S)- or (R)-3-methyl-2-phenylbutylamine in an organic solvent to produce a diastereomeric salt; and treating the diastereomeric salt with an acid in a second solvent. In the method of the present invention, flurbiprofen having a desired absolute configuration can be obtained very efficiently without repeating the procedure for optical resolution a plurality of times.


Find Patent Forward Citations

Kamiyama, Shunji. (2007). Process for producing optically active flurbiprofen (U.S. Patent No. 7214820). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7214820

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