The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2007
Filed:
Jul. 06, 2000
Leonard A. Smith, Clarksburg, MD (US);
Michael P. Byrne, New Market, MD (US);
John L. Middlebrook, Middletown, MD (US);
Hugh Lapenotiere, Charlestown, WV (US);
Michael A. Clayton, Mt. Airy, MD (US);
Douglas R. Brown, Gaithersburg, MD (US);
Leonard A. Smith, Clarksburg, MD (US);
Michael P. Byrne, New Market, MD (US);
John L. Middlebrook, Middletown, MD (US);
Hugh Lapenotiere, Charlestown, WV (US);
Michael A. Clayton, Mt. Airy, MD (US);
Douglas R. Brown, Gaithersburg, MD (US);
United States of America as Represented by the Secretary of the Army, Washington, DC (US);
Abstract
This invention is directed to preparation and expression of synthetic genes encoding polypeptides containing protective epitopes of botulinum neurotoxin (BoNT). The invention is also directed to production of immunogenic peptides encoded by the synthetic genes, as weel as recovery and purification of the immunogenic peptides from recombinant organisms. The invention is also directed to methods of vaccination against botulism using the expressed peptides.